Package 'UpSetR'

Title: A More Scalable Alternative to Venn and Euler Diagrams for Visualizing Intersecting Sets
Description: Creates visualizations of intersecting sets using a novel matrix design, along with visualizations of several common set, element and attribute related tasks (Conway 2017) <doi:10.1093/bioinformatics/btx364>.
Authors: Jake Conway [cre], Nils Gehlenborg [aut]
Maintainer: Jake Conway <[email protected]>
License: MIT + file LICENSE
Version: 1.4.0
Built: 2024-08-13 13:18:18 UTC
Source: https://github.com/hms-dbmi/upsetr

Help Index


Element query for queries parameter

Description

A query paramter to visualize specific elements of interest if queries = active (in custom plots only)

Usage

elements(func, query, ...)

Arguments

func

A functions provided internally

query

Input from the queries parameter assigned to the element function.

...

Additional parameters to be supplied internally

Note

See examples section of upset function on how to use this function in the queries parameter.


Expression to UpSetR converters

Description

A function to convert an expression to a data frame compatible with UpSetR.

Usage

fromExpression(input)

Arguments

input

An vector (expression) to be converted to an input compatible with UpSetR

Note

See "Basic Usage" vignette for an example on how to use this function in UpSetR.


List of named vectors to UpSetR converter

Description

A function to convert a list of named vectors to a data frame compatible with UpSetR.

Usage

fromList(input)

Arguments

input

A list of named vectors to be converted to a data frame compatible with UpSetR

Note

See "Basic Usage" vignette for an example on how to use this function in UpSetR.


Histogram for custom plot

Description

A pre-made histogram that can be added to custom.plot parameter.

Usage

histogram(mydata, x)

Arguments

mydata

A data set containing intersection data provided internally

x

The x aesthetic of for the histogram plot

Note

See examples section for upset function on how to use custom.plot parameter


Intersection query for queries parameter

Description

A query paramter to visualize elements contained in specific intersections

Usage

intersects(func, query, ...)

Arguments

func

A functions provided internally

query

Input from the queries parameter assigned to the intersection function.

...

Additional parameters to be applied internally

Note

See examples section of upset function on how to use this function in the queries parameter.


Scatterplot for customplot

Description

A pre-made scatter plot that can be added to the custom.plot parameter.

Usage

scatter_plot(mydata, x, y)

Arguments

mydata

A data set containing intersection data provided internally

x

The x aesthetic for the scatter plot

y

The y aesthetic for the scatter plot

Note

See examples section for upset function on how to use custom.plot parameter.


UpSetR Plot

Description

Visualization of set intersections using novel UpSet matrix design.

Usage

upset(
  data,
  nsets = 5,
  nintersects = 40,
  sets = NULL,
  keep.order = F,
  set.metadata = NULL,
  intersections = NULL,
  matrix.color = "gray23",
  main.bar.color = "gray23",
  mainbar.y.label = "Intersection Size",
  mainbar.y.max = NULL,
  sets.bar.color = "gray23",
  plot.title = NA,
  sets.x.label = "Set Size",
  point.size = 2.2,
  line.size = 0.7,
  mb.ratio = c(0.7, 0.3),
  expression = NULL,
  att.pos = NULL,
  att.color = main.bar.color,
  order.by = c("freq", "degree"),
  decreasing = c(T, F),
  show.numbers = "yes",
  number.angles = 0,
  number.colors = NULL,
  group.by = "degree",
  cutoff = NULL,
  queries = NULL,
  query.legend = "none",
  shade.color = "gray88",
  shade.alpha = 0.25,
  matrix.dot.alpha = 0.5,
  empty.intersections = NULL,
  color.pal = 1,
  boxplot.summary = NULL,
  attribute.plots = NULL,
  scale.intersections = "identity",
  scale.sets = "identity",
  text.scale = 1,
  set_size.angles = 0,
  set_size.show = FALSE,
  set_size.numbers_size = NULL,
  set_size.scale_max = NULL
)

Arguments

data

Data set

nsets

Number of sets to look at

nintersects

Number of intersections to plot. If set to NA, all intersections will be plotted.

sets

Specific sets to look at (Include as combinations. Ex: c("Name1", "Name2"))

keep.order

Keep sets in the order entered using the sets parameter. The default is FALSE, which orders the sets by their sizes.

set.metadata

Metadata that offers insight to an attribute of the sets. Input should be a data frame where the first column is set names, and the remaining columns are attributes of those sets. To learn how to use this parameter it is highly suggested to view the set metadata vignette. The link can be found on the package's GitHub page.

intersections

Specific intersections to include in plot entered as a list of lists. Ex: list(list("Set name1", "Set name2"), list("Set name1", "Set name3")). If data is entered into this parameter the only data shown on the UpSet plot will be the specific intersections listed.

matrix.color

Color of the intersection points

main.bar.color

Color of the main bar plot

mainbar.y.label

The y-axis label of the intersection size bar plot

mainbar.y.max

The maximum y value of the intersection size bar plot scale. May be useful when aligning multiple UpSet plots horizontally.

sets.bar.color

Color of set size bar plot

plot.title

Title of UpSetR plot

sets.x.label

The x-axis label of the set size bar plot

point.size

Size of points in matrix plot

line.size

Width of lines in matrix plot

mb.ratio

Ratio between matrix plot and main bar plot (Keep in terms of hundredths)

expression

Expression to subset attributes of intersection or element query data. Enter as string (Ex: "ColName > 3")

att.pos

Position of attribute plot. If NULL or "bottom" the plot will be at below UpSet plot. If "top" it will be above UpSet plot

att.color

Color of attribute histogram bins or scatterplot points for unqueried data represented by main bars. Default set to color of main bars.

order.by

How the intersections in the matrix should be ordered by. Options include frequency (entered as "freq"), degree, or both in any order.

decreasing

How the variables in order.by should be ordered. "freq" is decreasing (greatest to least) and "degree" is increasing (least to greatest)

show.numbers

Show numbers of intersection sizes above bars

number.angles

The angle of the numbers atop the intersection size bars

number.colors

The colors of the numbers atop the intersection size bars

group.by

How the data should be grouped ("degree" or "sets")

cutoff

The number of intersections from each set (to cut off at) when aggregating by sets

queries

Unified query of intersections, elements, and custom row functions. Entered as a list that contains a list of queries. query is the type of query being conducted. params are the parameters of the query (if any). color is the color of the points on the plot that will represent the query. If no color is selected one will be provided automatically. active takes TRUE or FALSE, and if TRUE, it will overlay the bars present with the results from the query. If FALSE a tick mark will indicate the intersection size. See examples section on how to do this.

query.legend

Position query legend on top or bottom of UpSet plot

shade.color

Color of row shading in matrix

shade.alpha

Transparency of shading in matrix

matrix.dot.alpha

Transparency of the empty intersections points in the matrix

empty.intersections

Additionally display empty sets up to nintersects

color.pal

Color palette for attribute plots

boxplot.summary

Boxplots representing the distribution of a selected attribute for each intersection. Select attributes by entering a character vector of attribute names (e.g. c("Name1", "Name2")). The maximum number of attributes that can be entered is 2.

attribute.plots

Create custom ggplot using intersection data represented in the main bar plot. Prior to adding custom plots, the UpSet plot is set up in a 100 by 100 grid. The attribute.plots parameter takes a list that contains the number of rows that should be allocated for the custom plot, and a list of plots with specified positions. nrows is the number of rows the custom plots should take up. There is already 100 allocated for the custom plot. plots takes a list that contains a function that returns a custom ggplot and the x and y aesthetics for the function. ncols is the number of columns that your ggplots should take up. See examples for how to add custom ggplots.

scale.intersections

The scale to be used for the intersection sizes. Options: "identity", "log10", "log2"

scale.sets

The scale to be used for the set sizes. Options: "identity", "log10", "log2"

text.scale

Numeric, value to scale the text sizes, applies to all axis labels, tick labels, and numbers above bar plot. Can be a universal scale, or a vector containing individual scales in the following format: c(intersection size title, intersection size tick labels, set size title, set size tick labels, set names, numbers above bars)

set_size.angles

Numeric, angle to rotate the set size plot x-axis text

set_size.show

Logical, display the set sizes on the set size bar chart

set_size.numbers_size

If set_size.show is TRUE, adjust the size of the numbers

set_size.scale_max

Increase the maximum of set size scale

Details

Visualization of set data in the layout described by Lex and Gehlenborg in http://www.nature.com/nmeth/journal/v11/n8/abs/nmeth.3033.html. UpSet also allows for visualization of queries on intersections and elements, along with custom queries queries implemented using Hadley Wickham's apply function. To further analyze the data contained in the intersections, the user may select additional attribute plots to be displayed alongside the UpSet plot. The user also has the the ability to pass their own plots into the function to further analyze data belonging to queries of interest. Most aspects of the UpSet plot are customizable, allowing the user to select the plot that best suits their style. Depending on how the features are selected, UpSet can display between 25-65 sets and between 40-100 intersections.

Note

Data set must be formatted as described on the original UpSet github page: http://github.com/VCG/upset/wiki.

References

Lex et al. (2014). UpSet: Visualization of Intersecting Sets IEEE Transactions on Visualization and Computer Graphics (Proceedings of InfoVis 2014), vol 20, pp. 1983-1992, (2014). http://people.seas.harvard.edu/~alex/papers/2014_infovis_upset.pdf

Lex and Gehlenborg (2014). Points of view: Sets and intersections. Nature Methods 11, 779 (2014). http://www.nature.com/nmeth/journal/v11/n8/abs/nmeth.3033.html

See Also

Original UpSet Website: http://vcg.github.io/upset/about/

UpSetR github for additional examples: http://github.com/hms-dbmi/UpSetR

Examples

movies <- read.csv( system.file("extdata", "movies.csv", package = "UpSetR"), header=TRUE, sep=";" )

require(ggplot2); require(plyr); require(gridExtra); require(grid);

between <- function(row, min, max){
  newData <- (row["ReleaseDate"] < max) & (row["ReleaseDate"] > min)
}

plot1 <- function(mydata, x){
  myplot <- (ggplot(mydata, aes_string(x= x, fill = "color"))
            + geom_histogram() + scale_fill_identity()
            + theme(plot.margin = unit(c(0,0,0,0), "cm")))
}

plot2 <- function(mydata, x, y){
  myplot <- (ggplot(data = mydata, aes_string(x=x, y=y, colour = "color"), alpha = 0.5)
            + geom_point() + scale_color_identity()
            + theme_bw() + theme(plot.margin = unit(c(0,0,0,0), "cm")))
}

attributeplots <- list(gridrows = 55,
                  plots = list(list(plot = plot1, x= "ReleaseDate",  queries = FALSE),
                         list(plot = plot1, x= "ReleaseDate", queries = TRUE),
                         list(plot = plot2, x = "ReleaseDate", y = "AvgRating", queries = FALSE),
                         list(plot = plot2, x = "ReleaseDate", y = "AvgRating", queries = TRUE)),
                   ncols = 3)

upset(movies, nsets = 7, nintersects = 30, mb.ratio = c(0.5, 0.5),
      order.by = c("freq", "degree"), decreasing = c(TRUE,FALSE))

upset(movies, sets = c("Drama", "Comedy", "Action", "Thriller", "Western", "Documentary"),
      queries = list(list(query = intersects, params = list("Drama", "Action")),
                list(query = between, params = list(1970, 1980), color = "red", active = TRUE)))

upset(movies, attribute.plots = attributeplots,
     queries = list(list(query = between, params = list(1920, 1940)),
                    list(query = intersects, params = list("Drama"), color= "red"),
                    list(query = elements, params = list("ReleaseDate", 1990, 1991, 1992))),
      main.bar.color = "yellow")